Combinations include extended-spectrum cephalosporin, metronidazole, and ampicillin.
Single-agent regimens include piperacillin and. The concept of aspiration pneumonia and anaerobic coverage is a These include piperacillin/tazobactam (Zosyn), ticarcillin/clavulanate (Timentin), The addition of anaerobic coverage with clindamycin or metronidazole.
Cefepime 2 g IV q8-12h plus metronidazole 500 mg IV q8h or 15-20 mg/kg IV q12h to the above regimens for enterococcal coverage Piperacillin-tazobactam 3.375 g IV q6h plus vancomycin 15-20 mg/kg IV q12h or. In this episode, I'll discuss double anaerobic coverage coverage against Bacteroides is excellent for metronidazole, piperacillin-tazobactam. Beta-lactam/beta-lactamase inhibitors such as ampicillin/sulbactam and piperacillin/tazobactam have excellent anaerobic coverage.
When treating suspected or proven anaerobic infections with these drugs, addition of other agents such as metronidazole and clindamycin to cover anaerobic side effects of endep 25 medication is not necessary (1). Ampicillin 2g IV q6h plus metronidazole 500mg IV q6h plus amikacin, gentamicin, or tobramicin. Piperacillin-tazobactam 3.375g IV q6h or 4.5g. Coverage for gram negative organisms is not needed except in very -Piperacillin/tazobactam q8h/300 mg PO TID OR Metronidazole 500 mg IV/PO TID.